Telomeres: More than chromosomal non-sticking ends
نویسندگان
چکیده
منابع مشابه
T-cell integrins: more than just sticking points.
T cells use integrins in essentially all of their functions. They use integrins to migrate in and out of lymph nodes and, following infection, to migrate into other tissues. At the beginning of an immune response, integrins also participate in the immunological synapse formed between T cells and antigen-presenting cells. Because the ligands for integrins are widely expressed, integrin activity ...
متن کاملFull-length cDNAs: more than just reaching the ends.
The development of functional genomic resources is essential to understand and utilize information generated from genome sequencing projects. Central to the development of this technology is the creation of high-quality cDNA resources and improved technologies for analyzing coding and noncoding mRNA sequences. The isolation and mapping of cDNAs is an entrée to characterizing the information tha...
متن کاملAre COVID-19 Protective Behaviours and Risk Perception More Common in Diabetic Women than Non-Diabetics?
Objective: Diabetic patients are more likely to be infected and are at the higher risk of morbidity and mortality in COVID-19 pandemic. The aim of this study was to compare the preventive behaviours and perceived risk of COVID-19 in women with and without type 2 diabetes mellitus (T2DM). Materials and Methods: The analytical cross-sectional study was conducted from June to July 2020 on 151 par...
متن کاملTelomeres and double-strand breaks - all's well that "ends" well. ...
Bailey, S. Telomeres and Double-Strand Breaks - All's Well that "Ends" Well. ... Radiat. Res. 169, 1-7 (2008). Sometimes one's life (including one's science) makes a lot more sense when viewed from the perspective of time, reflected back on over a number of years. That has indeed been the case for me. Strangely enough, the story begins with chromosomes and "ends" with telomeres, both at Colorad...
متن کاملFingering the Ends How to Make New Telomeres
Telomerase-mediated healing of broken chromosomes gives rise to terminal deletions and is repressed in most organisms. In ciliated protozoa, however, chromosome fragmentation and de novo telomere addition are part of the developmental program. Work by in this issue of Cell indicates that in Euplotes crassus, this is mediated through switching between different telomerase reverse transcriptase i...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecular Reproduction and Development
سال: 2000
ISSN: 1040-452X,1098-2795
DOI: 10.1002/1098-2795(200009)57:1<2::aid-mrd2>3.0.co;2-r